ZNF608 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
ZNF608
History
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timeline
title Publication timing
2013-08-15 : Morin : DLBCL
2017-01-26 : Krysiak : FL
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
![FL](https://github.com/morinlab/LLMPP/wiki/images/icons/FL_tier2.png) |
2 |
relevance in FL not firmly established[@krysiakRecurrentSomaticMutations2017b] |
![DLBCL](https://github.com/morinlab/LLMPP/wiki/images/icons/DLBCL_tier1.png) |
1 |
high-confidence DLBCL gene[@morinMutationalStructuralAnalysis2013; @reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
6.12 |
DLBCL |
Schmitz cohort |
9.36 |
DLBCL |
Reddy cohort |
8.11 |
DLBCL |
Chapuy cohort |
7.69 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
0.986 |
0.000 |
DLBCL |
No |
No |
1.714 |
3.638 |
FL |
No |
No |
1.867 |
4.218 |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/ZNF608_NM_020747.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/ZNF608.svg)
ZNF608 Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/ZNF608_by_pathology.svg)
References