ZCCHC7 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
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ZCCHC7
History
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timeline
title Publication timing
2018-10-01 : Arthur : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
![DLBCL](https://github.com/morinlab/LLMPP/wiki/images/icons/DLBCL_tier2.png) |
2-a |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@arthurGenomewideDiscoverySomatic2018] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
0.57 |
DLBCL |
Schmitz cohort |
0.85 |
DLBCL |
Reddy cohort |
0.40 |
DLBCL |
Chapuy cohort |
2.56 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
Yes |
No |
2.124 |
0 |
DLBCL |
Yes |
No |
1.558 |
0 |
FL |
Yes |
No |
0.000 |
0 |
aSHM regions
chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
chr9 |
37192080 |
37207549 |
intron-4 |
intron |
chr9 |
37275952 |
37306152 |
intron-2 |
intron |
chr9 |
37312655 |
37328260 |
intron-3 |
intron |
chr9 |
37329706 |
37340398 |
intron-1 |
intron |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/ZCCHC7_NM_032226.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/ZCCHC7.svg)
ZCCHC7 Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/ZCCHC7_by_pathology.svg)
References