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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

ZC3H12A

History

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timeline
    title Publication timing
2018-05-01 : Chapuy : DLBCL
2018-10-01 : Arthur : DLBCL

Relevance tier by entity

Entity	Tier	Description
	2	relevance in MCL not firmly established
	1	high-confidence DLBCL gene [@chapuyMolecularSubtypesDiffuse2018b; @arthurGenomewideDiscoverySomatic2018]
	2	relevance in FL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	2.68
DLBCL	Schmitz cohort	5.96
DLBCL	Reddy cohort	3.10
DLBCL	Chapuy cohort	4.70
FL	GAMBL genomes	0.46

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.000	0.000
DLBCL	No	No	2.488	18.944
FL	No	No	0.000	0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

ZC3H12A Expression

References