YY1 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
YY1
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
2018-05-01 : Chapuy : DLBCL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017; @chapuyMolecularSubtypesDiffuse2018b] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.15 |
| DLBCL | Schmitz cohort | 4.26 |
| DLBCL | Reddy cohort | 1.10 |
| DLBCL | Chapuy cohort | 3.85 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 6.553 | 0.000 |
| DLBCL | No | No | 3.473 | 57.733 |
| FL | No | No | 3.554 | 61.850 |
[!WARNING] Mutations in this gene were reported to be inflated in the original results according to Dreval K
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
YY1 Expression
