XPO1 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @jardinRecurrentMutationsExportin2016, @mareschalWholeExomeSequencing2016, @reddyGeneticFunctionalDrivers2017,
Experimental Evidence
Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a new function (NEO).[@miloudiXPO1E571KMutationModifies2020]
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
Mutation pattern and selective pressure estimates
XPO1 Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr2 | 61719471 | T>C | E571G |
| chr2 | 61719472 | C>T | E571K |
include:tables/browser_XPO1.md
Expression
include:tables/mermaid_XPO1.md