WAC - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
WAC
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
History
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timeline
title Publication timing
2012-08-27 : Rossi : MZL
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in MZL not firmly established[@rossiCodingGenomeSplenic2012c] |
 |
3 | Retired, Failed QC[@reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 2.68 |
| DLBCL | Schmitz cohort | 3.40 |
| DLBCL | Reddy cohort | 1.20 |
| DLBCL | Chapuy cohort | 1.28 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 0.957 | 0 |
| DLBCL | No | No | 1.590 | 0 |
| FL | No | No | 0.000 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
WAC Expression
All Mutations
Reddy_2232T Reddy_2619T Reddy_2698T Reddy_2769T Reddy_2791T Reddy_2892T Reddy_2898T Reddy_2919T Reddy_2931T Reddy_2933T Reddy_2934T Reddy_2936T Reddy_2953T Reddy_2999T Reddy_3456T Reddy_3480T Reddy_3653T Reddy_3704T Reddy_3721T Reddy_3750T Reddy_3758T Reddy_3977T