UBR5 - morinlab/LLMPP GitHub Wiki

---

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @reddyGeneticFunctionalDrivers2017, @pararajalingamCodingNoncodingDrivers2020, @zhangGeneticHeterogeneityDiffuse2013,

TOC

Overview

Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHeterogeneityDiffuse2013] and by the same group in a subsequent study.[@reddyGeneticFunctionalDrivers2017] It remains in Tier 2 because other exome and genome-wide studies of DLBCL did not reproduce this observation.

Relevance tier by entity

include:tables/table1_UBR5.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

MCL

include:tables/MCL_UBR5.md

DLBCL

include:tables/DLBCL_UBR5.md

Mutation pattern and selective pressure estimates

include:tables/dnds_UBR5.md

include:tables/browser_UBR5.md

Expression

include:tables/mermaid_UBR5.md

References