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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

TTN

History

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timeline
    title Publication timing
      2022-07-06 : Burkhardt : BL

Relevance tier by entity

Entity	Tier	Description
	2	relevance in BL not firmly established[@burkhardtClinicalRelevanceMolecular2022b]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
BL	GAMBL genomes+capture	28.64
BL	Thomas cohort	NA
BL	Panea cohort	NA

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.000	0.000
DLBCL	No	No	0.921	1.537
FL	No	No	0.000	0.000

TTN Hotspots

Chromosome	Coordinate (hg19)	ref>alt	HGVSp
chr2	179638249	C>T	E2512K

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

TTN Expression

References