TRRAP - morinlab/LLMPP GitHub Wiki

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

TRRAP

History

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timeline
    title Publication timing
      2012-08-27 : Rossi : MZL
      2013-01-01 : Zhang : DLBCL
      2013-12-13 : Parry : DLBCL

Relevance tier by entity

Entity Tier Description
MZL 2 relevance in MZL not firmly established[@rossiCodingGenomeSplenic2012c]
DLBCL 3 Retired for DLBCL[@zhangGeneticHeterogeneityDiffuse2013]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.87
DLBCL Schmitz cohort 8.94
DLBCL Reddy cohort 3.50
DLBCL Chapuy cohort 5.98

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.571 0
DLBCL No No 1.296 0
FL No No 2.757 0

TRRAP Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr7 98509802 C>T S722F

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

TRRAP Expression

References