TRAF6 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @hubschmannMutationalMechanismsShaping2021,
Relevance tier by entity
include:tables/table1_TRAF6.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.34 |
| DLBCL | Schmitz cohort | 1.49 |
| DLBCL | Reddy cohort | 0.90 |
| DLBCL | Chapuy cohort | 1.28 |
Mutation pattern and selective pressure estimates
TRAF6 Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr11 | 36511924 | C>A | E345* |
| chr11 | 36511915 | G>A | Q348* |
| chr11 | 36511893 | C>T | W355* |
| chr11 | 36511892 | C>T | W355* |
include:tables/browser_TRAF6.md
Expression
All Mutations
SP116630 SP193005 SP193312 SP59456
include:tables/mermaid_TRAF6.md