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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

TRAF3

History

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timeline
    title Publication timing
      2011-07-31 : Pasqualucci : DLBCL
      2011-11-03 : Rossi : MZL
      2012-06-01 : Otto : PMBL

Relevance tier by entity

Entity	Tier	Description
	1	high-confidence PMBL/cHL/GZL gene[@ottoGeneticLesionsTRAF32012a]
	1	high-confidence MZL gene[@rossiAlterationBIRC3Multiple2011a]
	2	relevance in DLBCL not firmly established[@pasqualucciAnalysisCodingGenome2011]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	0.96
DLBCL	Schmitz cohort	1.49
DLBCL	Reddy cohort	0.90
DLBCL	Chapuy cohort	0.43

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.795	0
DLBCL	No	No	1.440	0
FL	No	No	0.000	0

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

TRAF3 Expression

References