TP53 - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @wildaInactivationARFMDM2p53Pathway2004, @lohrDiscoveryPrioritizationSomatic2012, @tiacciPervasiveMutationsJAKSTAT2018, @morinFrequentMutationHistonemodifying2011, @beaLandscapeSomaticMutations2013, @rossiCodingGenomeSplenic2012,

TOC

Experimental Evidence

Driver mutations affecting this gene in BL/FL/DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@katoUnderstandingFunctionstructureFunctionmutation2003]

Relevance tier by entity

include:tables/table1_TP53.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

DLBCL

include:tables/DLBCL_TP53.md

FL

include:tables/FL_TP53.md

BL

include:tables/BL_TP53.md

MCL

include:tables/MCL_TP53.md

Mutation pattern and selective pressure estimates

include:tables/dnds_TP53.md

include:tables/browser_TP53.md

Expression

include:tables/mermaid_TP53.md

References