TP53 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @wildaInactivationARFMDM2p53Pathway2004, @lohrDiscoveryPrioritizationSomatic2012, @tiacciPervasiveMutationsJAKSTAT2018, @morinFrequentMutationHistonemodifying2011, @beaLandscapeSomaticMutations2013, @rossiCodingGenomeSplenic2012,
Experimental Evidence
Driver mutations affecting this gene in BL/FL/DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@katoUnderstandingFunctionstructureFunctionmutation2003]
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
FL
BL
MCL
Mutation pattern and selective pressure estimates
include:tables/browser_TP53.md
Expression
include:tables/mermaid_TP53.md