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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

TOP2A

History

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timeline
    title Publication timing
      2012-10-04 : Schmitz : BL

Relevance tier by entity

Entity	Tier	Description
	2	relevance in BL not firmly established[@schmitzBurkittLymphomaPathogenesis2012]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
BL	GAMBL genomes+capture	1.62
BL	Thomas cohort	NA
BL	Panea cohort	NA

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	3.194	0
DLBCL	No	No	0.774	0
FL	No	No	0.000	0

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

TOP2A Expression

References