TFAP4 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @grandeGenomewideDiscoverySomatic2019,
Overview
Mutations in BL were first described by Grande et al.[@grandeGenomewideDiscoverySomatic2019]
Experimental Evidence
Driver mutations affecting this gene in BL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@toncUnexpectedSuppressionTumorigenesis2021]
Relevance tier by entity
include:tables/table1_TFAP4.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
BL
Mutation pattern and selective pressure estimates
include:tables/browser_TFAP4.md
Expression
include:tables/mermaid_TFAP4.md