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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

TAP1

History

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timeline
    title Publication timing
      2018-04-12 : Schmitz : DLBCL

Relevance tier by entity

Entity	Tier	Description
	1	high-confidence PMBL/cHL/GZL gene
	2	relevance in DLBCL not firmly established[@schmitzGeneticsPathogenesisDiffuse2018a]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	0.57
DLBCL	Schmitz cohort	3.62
DLBCL	Reddy cohort	NA
DLBCL	Chapuy cohort	2.56

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.986	0.000
DLBCL	No	No	0.632	0.000
FL	No	No	3.142	39.164

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

TAP1 Expression

References