SYK - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
SYK
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
History
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
3 | Retired, failed QC[@reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.53 |
| DLBCL | Schmitz cohort | 2.34 |
| DLBCL | Reddy cohort | 0.80 |
| DLBCL | Chapuy cohort | 0.43 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.281 | 0.00 |
| DLBCL | No | No | 3.818 | 12.94 |
| FL | No | No | 0.000 | 0.00 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
SYK Expression
All Mutations
Reddy_2079T Reddy_2228T Reddy_2261T Reddy_2599T Reddy_2761T Reddy_2766T Reddy_2874T Reddy_2922T Reddy_3610T Reddy_3627T Reddy_3637T Reddy_3698T Reddy_683T