RRAGC - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
RRAGC
History
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timeline
title Publication timing
2016-02-02 : Okosun : FL
2017-10-10 : Reddy : DLBCL
2021-05-05 : Hubschmann : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
|
1 |
high-confidence DLBCL gene[@reddyGeneticFunctionalDrivers2017;@hubschmannMutationalMechanismsShaping2021b ] |
|
1 |
high-confidence FL gene [@okosunRecurrentMTORC1activatingRRAGC2016a] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
1.72 |
DLBCL |
Schmitz cohort |
2.98 |
DLBCL |
Reddy cohort |
2.00 |
DLBCL |
Chapuy cohort |
0.43 |
FL |
GAMBL genomes |
10.85 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
0.000 |
0 |
DLBCL |
No |
No |
2.679 |
0 |
FL |
No |
Yes |
163.715 |
0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
RRAGC Expression
References