RRAGC - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @okosunRecurrentMTORC1activatingRRAGC2016, @reddyGeneticFunctionalDrivers2017, @hubschmannMutationalMechanismsShaping2021,

TOC

Experimental Evidence

Driver mutations affecting this gene in DLBCL/FL have been experimentally demonstrated to cause a gain of function (GOF).[@okosunRecurrentMTORC1activatingRRAGC2016]

Relevance tier by entity

include:tables/table1_RRAGC.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

DLBCL

include:tables/DLBCL_RRAGC.md

FL

include:tables/FL_RRAGC.md

Mutation pattern and selective pressure estimates

include:tables/dnds_RRAGC.md

include:tables/browser_RRAGC.md

Expression

include:tables/mermaid_RRAGC.md

References