RFX7 - morinlab/LLMPP GitHub Wiki

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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @grandeGenomewideDiscoverySomatic2019, @arthurGenomewideDiscoverySomatic2018,

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Overview

First described as mutated in BL in 2009 by Grande et al.[@grandeGenomewideDiscoverySomatic2019]

Experimental Evidence

Driver mutations affecting this gene in DLBCL/BL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@weberPiggyBacTransposonTools2019]

Relevance tier by entity

include:tables/table1_RFX7.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

DLBCL

include:tables/DLBCL_RFX7.md

BL

include:tables/BL_RFX7.md

Mutation pattern and selective pressure estimates

include:tables/dnds_RFX7.md

include:tables/browser_RFX7.md

Expression

include:tables/mermaid_RFX7.md

References