PTPRD - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
PTPRD
History
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timeline
title Publication timing
2016-09-08 : Spina : MZL
Relevance tier by entity
Entity |
Tier |
Description |
![MZL](https://github.com/morinlab/LLMPP/wiki/images/icons/MZL_tier1.png) |
1 |
high-confidence MZL gene[@spinaGeneticsNodalMarginal2016b] |
![PMBL](https://github.com/morinlab/LLMPP/wiki/images/icons/PMBL_tier1.png) |
1 |
high-confidence PMBL/cHL/GZL gene |
![DLBCL](https://github.com/morinlab/LLMPP/wiki/images/icons/DLBCL_tier1.png) |
2 |
low-confidence DLBCL gene |
![FL](https://github.com/morinlab/LLMPP/wiki/images/icons/FL_tier1.png) |
1 |
high-confidence FL gene |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
5.54 |
DLBCL |
Schmitz cohort |
7.66 |
DLBCL |
Reddy cohort |
5.21 |
DLBCL |
Chapuy cohort |
5.56 |
FL |
GAMBL genomes |
3.70 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
1.905 |
0.000 |
DLBCL |
No |
No |
0.969 |
0.000 |
FL |
No |
No |
1.549 |
3.769 |
PTPRD Hotspots
Chromosome |
Coordinate (hg19) |
ref>alt |
HGVSp |
chr9 |
8376670 |
T>G |
Q1481H |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/PTPRD_NM_002839.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/PTPRD.svg)
PTPRD Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/PTPRD_by_pathology.svg)
References