PTPN6 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @reddyGeneticFunctionalDrivers2017,
Experimental Evidence
Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@demosthenousLossFunctionMutations2015]
Relevance tier by entity
include:tables/table1_PTPN6.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
Mutation pattern and selective pressure estimates
include:tables/browser_PTPN6.md
Expression
include:tables/mermaid_PTPN6.md