PTEN - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @reddyGeneticFunctionalDrivers2017, @chapuyMolecularSubtypesDiffuse2018, @loveGeneticLandscapeMutations2012,

TOC

Experimental Evidence

Driver mutations affecting this gene in BL/DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@pfeiferPTENLossDefines2013]

Relevance tier by entity

include:tables/table1_PTEN.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

DLBCL

include:tables/DLBCL_PTEN.md

BL

include:tables/BL_PTEN.md

Mutation pattern and selective pressure estimates

include:tables/dnds_PTEN.md

include:tables/browser_PTEN.md

Expression

include:tables/mermaid_PTEN.md

References