PPP4C - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
PPP4C
History
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timeline
title Publication timing
2021-05-05 : Hübschmann : FL
Relevance tier by entity
Entity |
Tier |
Description |
![FL](https://github.com/morinlab/LLMPP/wiki/images/icons/FL_tier2.png) |
2 |
relevance in FL not firmly established[@hubschmannMutationalMechanismsShaping2021b] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
FL |
GAMBL genomes |
2.08 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
2.143 |
25.647 |
DLBCL |
No |
No |
6.715 |
0.000 |
FL |
No |
No |
43.394 |
0.000 |
PPP4C Hotspots
Chromosome |
Coordinate (hg19) |
ref>alt |
HGVSp |
chr16 |
30093814 |
G>A |
D54N |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/PPP4C_NM_002720.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/PPP4C.svg)
PPP4C Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/PPP4C_by_pathology.svg)
All Mutations
SP192997
SP116720
SP192997
SP59320
References