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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

PPP4C

History

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timeline
    title Publication timing
      2021-05-05 : Hübschmann : FL

Relevance tier by entity

Entity	Tier	Description
	2	relevance in FL not firmly established[@hubschmannMutationalMechanismsShaping2021b]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
FL	GAMBL genomes	2.08

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	2.143	25.647
DLBCL	No	No	6.715	0.000
FL	No	No	43.394	0.000

PPP4C Hotspots

Chromosome	Coordinate (hg19)	ref>alt	HGVSp
chr16	30093814	G>A	D54N

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

PPP4C Expression

All Mutations

SP192997 SP116720 SP192997 SP59320

References