PNPO - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @hubschmannMutationalMechanismsShaping2021,

TOC

Overview

Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]

Relevance tier by entity

include:tables/table1_PNPO.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 0.38
DLBCL Schmitz cohort 0.21
DLBCL Reddy cohort 0.30
DLBCL Chapuy cohort 0.85

Mutation pattern and selective pressure estimates

include:tables/dnds_PNPO.md

include:tables/browser_PNPO.md

Expression

All Mutations

SP192997 SP116610

include:tables/mermaid_PNPO.md

References