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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

PLCG2

History

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timeline
    title Publication timing
      2019-09-26 : Panea : BL

Relevance tier by entity

Entity	Tier	Description
	2	relevance in BL not firmly established[@paneaWholeGenomeLandscape2019]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
BL	GAMBL genomes+capture	3.0
BL	Thomas cohort	0.8
BL	Panea cohort	10.9

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.800	0.000
DLBCL	No	No	2.213	14.094
FL	No	No	1.491	0.000

PLCG2 Hotspots

Chromosome	Coordinate (hg19)	ref>alt	HGVSp
chr16	81819719	C>A	T42N

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

PLCG2 Expression

References