PIK3CD - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @zhangGeneticHeterogeneityDiffuse2013,
Relevance tier by entity
include:tables/table1_PIK3CD.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 3.82 |
| DLBCL | Schmitz cohort | 4.89 |
| DLBCL | Reddy cohort | 2.50 |
| DLBCL | Chapuy cohort | 2.14 |
Mutation pattern and selective pressure estimates
PIK3CD Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr1 | 9787030 | G>A | E1021K |
| chr1 | 9787040 | G>A | R1024H |
| chr1 | 9787043 | A>G | E1025G |
include:tables/browser_PIK3CD.md
Expression
All Mutations
Reddy_2141T Reddy_2153T Reddy_2158T Reddy_2161T Reddy_2162T Reddy_2247T Reddy_2263T Reddy_2273T Reddy_2448T Reddy_2449T Reddy_2606T Reddy_2626T Reddy_2632T Reddy_2684T Reddy_2709T Reddy_2719T Reddy_2766T Reddy_2776T Reddy_2777T Reddy_2781T Reddy_2806T Reddy_2815T Reddy_2884T Reddy_2886T Reddy_2899T Reddy_2915T Reddy_2934T Reddy_2951T Reddy_2952T Reddy_2995T Reddy_3382T Reddy_3386T Reddy_3396T Reddy_3398T Reddy_3429T Reddy_3431T Reddy_3432T Reddy_3444T Reddy_3447T Reddy_3451T Reddy_3454T Reddy_3458T Reddy_3460T Reddy_3464T Reddy_3496T Reddy_3505T Reddy_3523T Reddy_3528T Reddy_3580T Reddy_3582T Reddy_3597T Reddy_3603T Reddy_3638T Reddy_3662T Reddy_3683T Reddy_3819T Reddy_3900T Reddy_3911T Reddy_3914T Reddy_3927T Reddy_3948T Reddy_3960T Reddy_3974T
include:tables/mermaid_PIK3CD.md