PCLO - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @lohrDiscoveryPrioritizationSomatic2012,
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 16.44 |
| DLBCL | Schmitz cohort | 21.28 |
| DLBCL | Reddy cohort | 15.12 |
| DLBCL | Chapuy cohort | 23.08 |
| FL | GAMBL genomes | 9.24 |
Mutation pattern and selective pressure estimates
PCLO Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr7 | 82585303 | G>T | L1656I |
| chr7 | 82585302 | A>G | L1656P |
| chr7 | 82544727 | T>C | K4192R |
include:tables/browser_PCLO.md
Expression
include:tables/mermaid_PCLO.md