PAX5 - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @pasqualucciHypermutationMultipleProtooncogenes2001,

TOC

Relevance tier by entity

include:tables/table1_PAX5.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 3.63
DLBCL Schmitz cohort 3.19
DLBCL Reddy cohort 1.90
DLBCL Chapuy cohort 3.42

Mutation pattern and selective pressure estimates

include:tables/dnds_PAX5.md

aSHM regions

chr_name hg19_start hg19_end region regulatory_comment
chr9 37023396 37027663 intron-1 intron
chr9 37029849 37037154 TSS-1 active_promoter
chr9 37369209 37372160 distal-enhancer-1 enhancer
chr9 37382267 37385854 distal-enhancer-2 enhancer
chr9 37395932 37409239 distal-enhancer-3 enhancer

include:tables/browser_PAX5.md

Expression

include:tables/mermaid_PAX5.md

References