PAX5 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
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PAX5
History
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timeline
title Publication timing
2001-07-19 : Pasqualucci : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
|
2-a |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@pasqualucciHypermutationMultipleProtooncogenes2001a] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
3.63 |
DLBCL |
Schmitz cohort |
3.19 |
DLBCL |
Reddy cohort |
1.90 |
DLBCL |
Chapuy cohort |
3.42 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
Yes |
No |
6.750 |
0 |
DLBCL |
Yes |
Yes |
14.089 |
0 |
FL |
Yes |
No |
10.963 |
0 |
aSHM regions
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
PAX5 Expression
References