OSBPL10 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @arthurGenomewideDiscoverySomatic2018, @zhangGeneticHeterogeneityDiffuse2013, @schmitzGeneticsPathogenesisDiffuse2018,
Overview
OSBPL10 is one of a number of genes affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.
Relevance tier by entity
include:tables/table1_OSBPL10.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
include:tables/DLBCL_OSBPL10.md
Mutation pattern and selective pressure estimates
include:tables/dnds_OSBPL10.md
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr3 | 32020518 | 32024930 | TSS-1 | active_promoter |
include:tables/browser_OSBPL10.md
Expression
include:tables/mermaid_OSBPL10.md