NOL9 - morinlab/LLMPP GitHub Wiki

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

NOL9

History

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timeline
    title Publication timing
      2016-09-08 : Spina : MZL
      2018-04-12 : Schmitz : DLBCL

Relevance tier by entity

Entity Tier Description
MZL 1 high-confidence MZL gene[@spinaGeneticsNodalMarginal2016b]
DLBCL 1 high-confidence DLBCL gene[@schmitzGeneticsPathogenesisDiffuse2018a]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 4.97
DLBCL Schmitz cohort 6.81
DLBCL Reddy cohort 1.30
DLBCL Chapuy cohort 2.14

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 1.514 0
DLBCL No No 4.012 0
FL No No 2.619 0

NOL9 Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr1 6614187 G>C L126V
chr1 6614167 C>A Q132H

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

NOL9 Expression

References