NFKB2 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
NFKB2
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
History
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
2019-09-05 : Mottok : PMBL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b] |
 |
3 | Retired, Failed QC[@reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.53 |
| DLBCL | Schmitz cohort | 1.49 |
| DLBCL | Reddy cohort | 1.40 |
| DLBCL | Chapuy cohort | 2.56 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 1.937 | 0.00 |
| DLBCL | No | No | 0.861 | 8.02 |
| FL | No | No | 2.873 | 0.00 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
NFKB2 Expression
All Mutations
Reddy_2124T Reddy_2525T Reddy_2538T Reddy_2613T Reddy_2637T Reddy_2643T Reddy_2681T Reddy_2761T Reddy_2765T Reddy_2884T Reddy_2918T Reddy_3582T Reddy_3617T Reddy_3639T Reddy_3737T Reddy_3754T Reddy_3825T Reddy_3839T Reddy_3933T Reddy_3936T Reddy_3996T Reddy_695T