NCOR2 - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @schmitzBurkittLymphomaPathogenesis2012, @sarkozyMutationalLandscapeGray2021, @spinaGeneticsNodalMarginal2016,

TOC

Overview

Mutations in this gene are relatively rare in DLBCL overall but show a pattern of inactivation.

Relevance tier by entity

include:tables/table1_NCOR2.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
BL GAMBL genomes+capture 6.24
BL Thomas cohort NA
BL Panea cohort NA
DLBCL GAMBL genomes 2.10
DLBCL Schmitz cohort 5.74
DLBCL Reddy cohort 3.60
DLBCL Chapuy cohort 4.27

Mutation pattern and selective pressure estimates

include:tables/dnds_NCOR2.md

include:tables/browser_NCOR2.md

Expression

include:tables/mermaid_NCOR2.md

References