NCOR2 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @schmitzBurkittLymphomaPathogenesis2012, @sarkozyMutationalLandscapeGray2021, @spinaGeneticsNodalMarginal2016,
Overview
Mutations in this gene are relatively rare in DLBCL overall but show a pattern of inactivation.
Relevance tier by entity
include:tables/table1_NCOR2.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 6.24 |
| BL | Thomas cohort | NA |
| BL | Panea cohort | NA |
| DLBCL | GAMBL genomes | 2.10 |
| DLBCL | Schmitz cohort | 5.74 |
| DLBCL | Reddy cohort | 3.60 |
| DLBCL | Chapuy cohort | 4.27 |
Mutation pattern and selective pressure estimates
include:tables/browser_NCOR2.md
Expression
include:tables/mermaid_NCOR2.md