MYBPC2 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
MYBPC2
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2018-04-12 : Schmitz : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
![DLBCL](https://github.com/morinlab/LLMPP/wiki/images/icons/DLBCL_tier2.png) |
2 |
relevance in DLBCL not firmly established[@schmitzGeneticsPathogenesisDiffuse2018a] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
0.57 |
DLBCL |
Schmitz cohort |
3.40 |
DLBCL |
Reddy cohort |
2.80 |
DLBCL |
Chapuy cohort |
1.71 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
1.437 |
6.011 |
DLBCL |
No |
No |
0.653 |
0.000 |
FL |
No |
No |
4.460 |
0.000 |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/MYBPC2_NM_004533.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/MYBPC2.svg)
MYBPC2 Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/MYBPC2_by_pathology.svg)
References