MYB - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
MYB
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
History
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
2019-08-20 : Desch : PMBL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in PMBL/cHL/GZL not firmly established[@deschGenotypingCirculatingTumor2020] |
 |
3 | Retired, Failed QC |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 0.57 |
| DLBCL | Schmitz cohort | 2.13 |
| DLBCL | Reddy cohort | 1.10 |
| DLBCL | Chapuy cohort | 0.85 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.555 | 0 |
| DLBCL | No | No | 0.000 | 0 |
| FL | No | No | 2.377 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
MYB Expression
All Mutations
Reddy_2120T Reddy_2137T Reddy_2140T Reddy_2190T Reddy_2450T Reddy_2680T Reddy_2895T Reddy_2935T Reddy_3394T Reddy_3485T Reddy_3755T Reddy_3766T Reddy_3779T Reddy_3783T Reddy_3846T Reddy_3852T Reddy_3948T Reddy_3961T Reddy_3978T Reddy_3990T