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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

MPDZ

History

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timeline
    title Publication timing
      2013-08-15 : Morin : DLBCL
      2015-02-12 : Reichel : PMBL

Relevance tier by entity

Entity	Tier	Description
	2	relevance in PMBL/cHL/GZL not firmly established[@reichelFlowSortingExome2015a]
	2	relevance in DLBCL not firmly established[@morinMutationalStructuralAnalysis2013]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	6.31
DLBCL	Schmitz cohort	11.70
DLBCL	Reddy cohort	5.61
DLBCL	Chapuy cohort	2.99

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	2.932	8.789
DLBCL	No	No	0.632	1.772
FL	No	No	2.769	0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

MPDZ Expression

All Mutations

DLBCL[@morinMutationalStructuralAnalysis2013]

RG054 RG064 RG081 RG115 RG130

References