MGEA5 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @hubschmannMutationalMechanismsShaping2021,
Overview
Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]
Relevance tier by entity
include:tables/table1_MGEA5.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| FL | GAMBL genomes | 1.85 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 1.383 | 0 |
| DLBCL | No | No | 2.152 | 0 |
| FL | No | No | 3.398 | 0 |
include:tables/browser_MGEA5.md
Expression
All Mutations
include:tables/mermaid_MGEA5.md