MGEA5 - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @hubschmannMutationalMechanismsShaping2021,

TOC

Overview

Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]

Relevance tier by entity

include:tables/table1_MGEA5.md

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
FL GAMBL genomes 1.85

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 1.383 0
DLBCL No No 2.152 0
FL No No 3.398 0

include:tables/browser_MGEA5.md

Expression

All Mutations

SP193655 SP116618 SP116649

include:tables/mermaid_MGEA5.md

References