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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

MAP4K4

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

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timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL

Relevance tier by entity

Entity	Tier	Description
	3	Retired, Failed QC[@reddyGeneticFunctionalDrivers2017]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	1.15
DLBCL	Schmitz cohort	1.49
DLBCL	Reddy cohort	2.10
DLBCL	Chapuy cohort	1.28

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	1.518	0.000
DLBCL	No	No	4.689	6.978
FL	No	No	0.000	0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

MAP4K4 Expression

All Mutations

Reddy_2046T Reddy_2112T Reddy_2148T Reddy_2156T Reddy_2263T Reddy_2575T Reddy_2639T Reddy_2698T Reddy_2706T Reddy_2715T Reddy_2923T Reddy_3382T Reddy_3446T Reddy_3503T Reddy_3527T Reddy_3529T Reddy_3539T Reddy_3602T Reddy_3607T Reddy_3610T Reddy_3627T Reddy_3628T Reddy_3635T Reddy_3756T Reddy_3771T Reddy_3783T Reddy_3816T Reddy_3836T Reddy_3904T Reddy_3929T Reddy_3958T Reddy_3963T Reddy_3995T

References