MAGEC1 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
MAGEC1
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2023-07-26 : Russler : FL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in FL not firmly established[@russler-germainMutationsAssociatedProgression2023b] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| FL | GAMBL genomes | 1.85 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | Yes | 26.895 | 0.000 |
| DLBCL | No | No | 1.032 | 4.703 |
| FL | No | No | 0.000 | 0.000 |
MAGEC1 Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chrX | 140993821 | T>G | L211V |
| chrX | 140993827 | A>C | I213L |
| chrX | 140994066 | G>C | Q292H |
| chrX | 140994280 | A>G | T364A |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
MAGEC1 Expression
