LRRN3 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
LRRN3
History
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timeline
title Publication timing
2013-01-01 : Zhang : DLBCL
2013-08-15 : Morin : DLBCL
2021-04-01 : Sarkozy : PMBL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in PMBL/cHL/GZL not firmly established[@sarkozyMutationalLandscapeGray2021a] |
 |
1 | High-confidence DLBCL gene [@zhangGeneticHeterogeneityDiffuse2013; @morinMutationalStructuralAnalysis2013] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 8.22 |
| DLBCL | Schmitz cohort | 8.09 |
| DLBCL | Reddy cohort | 6.51 |
| DLBCL | Chapuy cohort | 6.84 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.141 | 0 |
| DLBCL | No | No | 2.591 | 0 |
| FL | No | No | 0.000 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
LRRN3 Expression
