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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

LIN54

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

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timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL

Relevance tier by entity

Entity	Tier	Description
	3	Retired, Failed QC

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	0.57
DLBCL	Schmitz cohort	2.13
DLBCL	Reddy cohort	0.90
DLBCL	Chapuy cohort	0.85

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.770	7.752
DLBCL	No	No	1.385	26.297
FL	No	No	0.000	0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

LIN54 Expression

All Mutations

Reddy_2164T Reddy_2225T Reddy_2473T Reddy_2634T Reddy_2768T Reddy_2899T Reddy_3403T Reddy_3419T Reddy_3493T Reddy_3608T Reddy_3636T Reddy_3813T Reddy_3827T Reddy_4000T

References