IKBKB - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
IKBKB
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2011-11-03 : Rossi : MZL
2017-10-10 : Reddy : DLBCL
2019-12-10 : Wienand : PMBL
Relevance tier by entity
Entity |
Tier |
Description |
|
2 |
relevance in PMBL/cHL/GZL not firmly established[@wienandGenomicAnalysesFlowsorted2019b] |
|
2 |
relevance in MZL not firmly established[@rossiAlterationBIRC3Multiple2011a] |
|
2 |
relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
0.57 |
DLBCL |
Schmitz cohort |
2.98 |
DLBCL |
Reddy cohort |
1.10 |
DLBCL |
Chapuy cohort |
3.42 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
4.726 |
0 |
DLBCL |
No |
No |
1.593 |
0 |
FL |
No |
No |
3.189 |
0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
IKBKB Expression
References