IGLL5 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @deschGenotypingCirculatingTumor2020, @paneaWholeGenomeLandscape2019, @russler-germainMutationsAssociatedProgression2023
Overview
Although IGLL5 is significantly mutated, Selective pressure analysis implies the gene is largely under negative selective pressure. It remains unclear whether any of the mutations in IGLL5 are relevant to DLBCL, BL or FL.
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
include:tables/DLBCL_IGLL5 include:tables/BL_IGLL5 include:tables/FL_IGLL5
Mutation pattern and selective pressure estimates
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr22 | 23229554 | 23232042 | TSS | NA |
include:tables/browser_IGLL5.md
Expression
include:tables/mermaid_IGLL5.md