HRAS - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
HRAS
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
History
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
title Publication timing
2017-07-27 : Jallades : MZL
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in MZL not firmly established[@jalladesExomeSequencingIdentifies2017] |
 |
3 | Retired, Failed QC[@reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | NA |
| DLBCL | Schmitz cohort | 0.21 |
| DLBCL | Reddy cohort | 0.70 |
| DLBCL | Chapuy cohort | 0.43 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 0 | 0 |
| DLBCL | No | No | 0 | 0 |
| FL | No | No | 0 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
HRAS Expression
All Mutations
Reddy_2463T Reddy_2565T Reddy_2637T Reddy_2643T Reddy_2659T Reddy_2777T Reddy_2912T Reddy_3385T Reddy_3417T Reddy_3482T Reddy_3496T Reddy_3537T Reddy_3580T Reddy_3631T Reddy_3726T Reddy_3751T Reddy_3811T Reddy_3845T Reddy_3851T