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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

HNRNPU

History

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timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL
      2019-09-26 : Panea : BL

Relevance tier by entity

Entity	Tier	Description
	1-a	aSHM target and high-confidence BL gene[@paneaWholeGenomeLandscape2019]
	1-a	aSHM target and high-confidence DLBCL gene[@reddyGeneticFunctionalDrivers2017]

Mutation incidence

Entity	source	frequency (%)
BL	GAMBL genomes+capture	5.77
BL	Thomas cohort	6.40
BL	Panea cohort	8.90
DLBCL	GAMBL genomes	2.49
DLBCL	Schmitz cohort	3.40
DLBCL	Reddy cohort	2.40
DLBCL	Chapuy cohort	3.42

Mutation pattern

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	Yes	Yes	1.081	27.052
DLBCL	Yes	No	1.712	0.000
FL	Yes	No	4.865	31.056

aSHM regions

chr_name	hg19_start	hg19_end	region	regulatory_comment
chr1	245023502	245029083	TSS	NA

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

References