HLA DQA1 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @hubschmannMutationalMechanismsShaping2021,
Overview
Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]
Relevance tier by entity
include:tables/table1_HLA-DQA1.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 0.38 |
| DLBCL | Schmitz cohort | 0.64 |
| DLBCL | Reddy cohort | 0.30 |
| DLBCL | Chapuy cohort | 1.28 |
Mutation pattern and selective pressure estimates
include:tables/dnds_HLA-DQA1.md
HLA-DQA1 Expression
All Mutations
SP116606 SP124957 SP192807 SP193072 SP193150 SP59424
include:tables/mermaid_HLA-DQA1.md