HIST1H3I - morinlab/LLMPP GitHub Wiki


bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

HIST1H3I

History

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timeline
    title Publication timing
      2017-01-26 : Krysiak : FL
      2019-09-26 : Panea : BL
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Relevance tier by entity

Entity Tier Description
BL 2 relevance in BL not firmly established[@paneaWholeGenomeLandscape2019]
FL 2 relevance in FL not firmly established[@krysiakRecurrentSomaticMutations2017b]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
BL GAMBL genomes+capture 0.46
BL Thomas cohort 0.00
BL Panea cohort 2.00
FL GAMBL genomes 1.15

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.000 0
DLBCL No No 5.397 0
FL No No 0.838 0

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

Representative Mutations

BL2

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References

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