FCRL3 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
FCRL3
Relevance tier by entity
| Entity |
Tier |
Description |
 |
2 |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity |
source |
frequency (%) |
| DLBCL |
GAMBL genomes |
2.49 |
| DLBCL |
Schmitz cohort |
3.40 |
| DLBCL |
Reddy cohort |
2.70 |
| DLBCL |
Chapuy cohort |
3.42 |
Mutation pattern and selective pressure estimates
| Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
| BL |
Yes |
No |
3.558 |
0.000 |
| DLBCL |
Yes |
No |
2.408 |
7.608 |
| FL |
Yes |
No |
0.000 |
0.000 |
aSHM regions
| chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
| chr2 |
157669490 |
157671299 |
TSS |
NA |
include:tables/browser_FCRL3.md
Expression
References