FAM102A - morinlab/LLMPP GitHub Wiki
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FAM102A
Relevance tier by entity
| Entity |
Tier |
Description |
 |
2-a |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity |
source |
frequency (%) |
| DLBCL |
GAMBL genomes |
2.49 |
| DLBCL |
Schmitz cohort |
3.83 |
| DLBCL |
Reddy cohort |
2.90 |
| DLBCL |
Chapuy cohort |
2.14 |
Mutation pattern and selective pressure estimates
| Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
| BL |
Yes |
No |
3.842 |
13.756 |
| DLBCL |
Yes |
No |
3.475 |
8.506 |
| FL |
Yes |
No |
10.512 |
0.000 |
aSHM regions
| chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
| chr9 |
130740362 |
130744800 |
TSS |
NA |
include:tables/browser_FAM102A.md
Expression
References