FAM102A - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
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FAM102A
Relevance tier by entity
Entity |
Tier |
Description |
![DLBCL](https://github.com/morinlab/LLMPP/wiki/images/icons/DLBCL_tier2.png) |
2-a |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
2.49 |
DLBCL |
Schmitz cohort |
3.83 |
DLBCL |
Reddy cohort |
2.90 |
DLBCL |
Chapuy cohort |
2.14 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
Yes |
No |
3.842 |
13.756 |
DLBCL |
Yes |
No |
3.475 |
8.506 |
FL |
Yes |
No |
10.512 |
0.000 |
aSHM regions
chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
chr9 |
130740362 |
130744800 |
TSS |
NA |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/FAM102A_NM_001035254.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/FAM102A.svg)
FAM102A Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/FAM102A_by_pathology.svg)
References