EZR - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
@deschGenotypingCirculatingTumor2020,
TOC
Relevance tier by entity
include:tables/table1_EZR.md
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity |
source |
frequency (%) |
| DLBCL |
GAMBL genomes |
1.34 |
| DLBCL |
Schmitz cohort |
2.13 |
| DLBCL |
Reddy cohort |
1.70 |
| DLBCL |
Chapuy cohort |
2.56 |
Mutation pattern and selective pressure estimates
| Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
| BL |
Yes |
No |
1.425 |
16.138 |
| DLBCL |
Yes |
No |
2.869 |
14.423 |
| FL |
Yes |
No |
3.576 |
0.000 |
aSHM regions
| chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
| chr6 |
159237903 |
159240216 |
TSS |
NA |
include:tables/browser_EZR.md
Expression
include:tables/mermaid_EZR.md
References