DICER1 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
DICER1
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
History
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
Relevance tier by entity
Entity | Tier | Description |
---|---|---|
![]() |
3 | Retired, Failed QC[@reddyGeneticFunctionalDrivers2017] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity | source | frequency (%) |
---|---|---|
DLBCL | GAMBL genomes | 1.34 |
DLBCL | Schmitz cohort | 2.34 |
DLBCL | Reddy cohort | 1.10 |
DLBCL | Chapuy cohort | 2.56 |
Mutation pattern and selective pressure estimates
Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
---|---|---|---|---|
BL | No | No | 0.609 | 0 |
DLBCL | No | No | 0.818 | 0 |
FL | No | No | 2.448 | 0 |
[!WARNING] Mutations in this gene were reported to be inflated in the original results according to Dreval K
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38