DCAF6 - morinlab/LLMPP GitHub Wiki
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.1 Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
| Entity | Tier | Description |
|---|---|---|
 |
3 | Retired, Failed QC[@reddyGeneticFunctionalDrivers2017] |
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.15 |
| DLBCL | Schmitz cohort | 2.34 |
| DLBCL | Reddy cohort | 1.30 |
| DLBCL | Chapuy cohort | 1.28 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 0.969 | 0 |
| DLBCL | No | No | 3.355 | 0 |
| FL | No | No | 0.000 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
Reddy_2085T Reddy_2124T Reddy_2125T Reddy_2133T Reddy_2162T Reddy_2209T Reddy_2215T Reddy_2236T Reddy_2242T Reddy_2467T Reddy_2468T Reddy_2565T Reddy_2606T Reddy_2611T Reddy_2766T Reddy_2772T Reddy_2829T Reddy_2919T Reddy_2921T Reddy_2999T Reddy_3409T Reddy_3432T Reddy_3479T Reddy_3536T Reddy_3548T Reddy_3607T Reddy_3635T Reddy_3646T Reddy_3679T Reddy_3688T Reddy_3825T Reddy_3915T Reddy_3919T Reddy_3920T Reddy_3974T Reddy_3978T Reddy_3981T Reddy_3987T Reddy_705T
